Center  for  Research  &  Education on Aging  (CREA)
University of California, Berkeley
 
 

logo

 




Release 10.00
 
logo     logo
Home          CREA          Timiras Award          Advisory Board          News          Resources          Aging Theories          Events          Donate


 
 
 
 
CREA

On November 8th, 2000 the Center for Research and Education on Aging (CREA) opened its doors. The center has a mission to "investigate the basic processes that cause aging, with the goal of improving and extending the human health span." CREA was the brainchild of Dr. Paul Segall, Ph.D. (1942-2003). His life long goal was to establish a center where the process of aging could be studied, understood and remediated. In 2000, Dr. Segall endowed CREA, and with Dr. Paola S. Timiras, M.D., Ph.D. (1923-2008) they established the Center at the University of California, Berkeley. Dr Timiras served as CREA's first chair person from 2000 until she passed away in 2008. The chair is currently held by Dr. George A. Brooks, Ph.D., Professor in the Department of Integrative Biology, at the University of California, Berkeley and the director of research is Steven A. Garan. CREA has supported many research projects such as the development of the Automated Imaging Microscope System (AIMS). AIMS was the first fully automated system that could scan large areas of tissue, reconstruct these large sections digitally as well as count cells that expressed different receptors and create a three dimensional volumetric model of the densities in those cell populations. AIMS helped researchers shed light on the effects of normal aging and caloric restriction on the hypothalamus. CREA supports research concerning computational systems biology approaches to neuroendocrine aging and is very active in many areas of aging research today.

logo

On July 15, 1999, The Lawrence Berkeley National Laboratory (LBNL), the University of California, Berkeley (UCB) and BioTime, signed an agreement creating a center for the study of the aging process. The center is now called the Center for Research and Education on Aging (CREA) and is a joint LBNL and UCB institution. Gathered at the signing ceremony are (left to right) Dr. Paul Segall, Dr. Paola Timiras , Dr. Judy Campisi, Dr. Mina Bissell, Dr. Ronald S. Barkin, and Dr. Don McQuade.

A link to a news item regarding CREA at the Lawrence Berkeley National Laboratory (LBNL).


                          

 
 



CREA's Mission

The mission of CREA is to investigate the basic processes that cause aging, with the goal of improving and extending human health span. CREA integrates the efforts of cell and molecular biologists, structural and computational biologists, geneticists, physiologists and public health professionals, who are the intellectual assets and resources of the University of California, Berkeley and the Lawrence Berkeley National Laboratory.

Never before in human history has so much been known about our bodies and the molecular mechanics that dictate their function. Even though people are living longer, with the percentage of Americans aged 65 and older rising from 4% in 1900 to 13% in 1998, little is known about why we become old. Among the challenges that greets the dawn of this millennium is the maintenance of good health and the postponement or reversal of old age and its debilitating diseases. In other words, how can we preserve youthfulness later in life?

By combining the keen minds of University of California scientists with the steady hands and eager intellect of its student body, the new Center for Research and Education in Aging (CREA) will rise to the challenge. The mission of CREA is to investigate the basic processes that cause aging, with the goal of improving and extending human health span. CREA integrates the efforts of cell and molecular biologists, structural and computational biologists, geneticists, physiologists and public health professionals, who are the intellectual assets and resources of the University of California, Berkeley and the Lawrence Berkeley National Laboratory. CREA is also associated with the Buck Institute for Age Research, a private nonprofit basic biomedical research institute located in Novato, California.

This unique partnership brings to the study of aging an approach that most medical schools cannot marshal because they focus on specific diseases and their treatments. Aging makes us vulnerable to disease and injury, but we do not know why. Research into the process responsible for aging remains seriously neglected. CREA is designed to create a research/education environment that fosters basic aging research and educates the next generations of scientists.

At CREA, innovative research, which too often goes unsupported, will be of prime interest. CREA will accelerate the discovery process of preventive and therapeutic interventions.

Support for CREA comes from competitive grants and the generosity of private donors. An endowment for CREA has been established by BioTime, Inc., a Berkeley, California-based biotechnology company, to better understand the mechanisms of aging and improve medical procedures focused on older patients.

By integrating the efforts of some of the world's best academic, government, and biotechnology industry laboratories, CREA will be a vital source for driving breakthroughs in improving health and youthfulness.