Pharmacogenomic and proteomic profiling of mitochondrial oxidative stress

• Total RNA used with dual color labeling

  • BMAP (11K), NIA (15K)

• Differential screening of tissues with varying doses of antioxidant drugs

• Subcellular fractionation for proteomic profiling

• Concordance of targets identified between aging (chronic-low) MOS (acute-high)?

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