The Genomics and Computational Biology (5T32HG000047-18) training program provides predoctoral training and research, emphasizing the cross-disciplinary nature of this rapidly advancing field. The program has three principal thrusts: the comparative and evolutionary analysis of genomes; the study of population level genetic variation; and the dissection of epigenetic and gene-regulatory networks. Trainees will take advantage of a rich training environment of seminars, retreats, and group meetings as well as a diverse set of formal course offerings that range from introductory to advanced methods in genomic biology. Research training will typically begin by the end of the second year, following an introductory period of laboratory rotations, coursework, and preliminary examinations. Progress of the trainees is evaluated by annual thesis reviews and regular meetings with mentors. The Program will train an average of 11 predoctoral students per year in genomics and computational biology.